Query: NC_014014:153837 Mycoplasma crocodyli MP145 chromosome, complete genome Lineage: Mycoplasma crocodyli; Mycoplasma; Mycoplasmataceae; Mycoplasmatales; Tenericutes; Bacteria General Information: Mycoplasma crocodyli was isolated from the joint of a crocodile with exudative polyarthritis. The siblingspecies of M. crocodyli, Mycoplasma alligatoris causes acute lethalprimary infection of susceptible hosts, notably American alligators.This pathogen is studied to understand the mechanisms and evolutionaryorigins of that virulence. A genome survey indicated that M. alligatorisuses sialidase (Nanl) and hyaluronidase (NagH) to generate fuel forglycolysis from host cell glycans. M. crocodyli, which does not causedisease in American alligators, possesses NagH but not Nanl, so damageto the host's extracellular matrix alone cannot explain the particularvirulence of M. alligatoris.
- Sequence; - BLASTN hit (Low score = Light, High score = Dark) - hypothetical protein; - cds: hover for description
General Information: A serum-resistant streptomycin-resistant proline-requiring strain isolated from a patient with disseminated gonococcal infections. Causes gonorrhea. One of two pathogenic Neisseria, this species causes the sexually transmitted disease (STD) gonorrhea, which is the leading reportable STD in adults in the USA. This human-specific organism colonizes and invades the mucosal surface of the urogenital epithelium, crosses the epithelial barrier, and ends up multiplying on the basement membrane. The Opa proteins are responsible for the opaque colony phenotype due to the tight junctions between adjacent Neisseria, and are also responsible for tight adherence to host cells. This organism, like Neisseria meningitidis, is also naturally competent for DNA uptake.