Query: NC_013928:174500 Streptococcus mutans NN2025, complete genome Lineage: Streptococcus mutans; Streptococcus; Streptococcaceae; Lactobacillales; Firmicutes; Bacteria General Information: This strain is a clinical serotype c strain isolated in Japan in 2002. Streptococci are Gram-positive, nonmotile, nonsporeforming, catalase-negative cocci that occur in pairs or chains. Members of this genus vary widely in pathogenic potential. Most streptococci are facultative anaerobes, and some are obligate anaerobes. Streptococcus mutans was first isolated in 1924 from human carious (cavities) lesions and is the main cause of tooth decay. This organism thrives in a bacterial community known as a dental plaque which forms on the surface of teeth. This organism has also been implicated in cases of infective endocarditis.
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General Information: Acinetobacter baumannii strain ACICU (also called H34) was isolated from an outbreak in an intensive care unit in Rome, Italy. This bacterium is commonly isolated from the hospital environment and hospitalized patients. It is an aquatic organism, and is often cultured from liquid medical samples such as respiratory secretions, wounds, and urine. Acinetobacter also colonizes irrigating solutions and intravenous solutions. Although it has low virulence, it is capable of causing infection. Most isolates recovered from patients represent colonization rather than infection. When infections do occur, they usually occur in the blood, or in organs with a high fluid content, such as the lungs or urinary tract.Infections by this organism are becoming increasingly problematic due to the high number of resistance genes found in clinical isolates. Some strains are now resistant to all known antibiotics. Most of these genes appear to have been transferred horizontally from other organisms.