Query: NC_013928:797714 Streptococcus mutans NN2025, complete genome
Lineage: Streptococcus mutans; Streptococcus; Streptococcaceae; Lactobacillales; Firmicutes; Bacteria
General Information: This strain is a clinical serotype c strain isolated in Japan in 2002. Streptococci are Gram-positive, nonmotile, nonsporeforming, catalase-negative cocci that occur in pairs or chains. Members of this genus vary widely in pathogenic potential. Most streptococci are facultative anaerobes, and some are obligate anaerobes. Streptococcus mutans was first isolated in 1924 from human carious (cavities) lesions and is the main cause of tooth decay. This organism thrives in a bacterial community known as a dental plaque which forms on the surface of teeth. This organism has also been implicated in cases of infective endocarditis.
Subject: NC_020995:477765 Enterococcus casseliflavus EC20, complete genome
Lineage: Enterococcus casseliflavus; Enterococcus; Enterococcaceae; Lactobacillales; Firmicutes; Bacteria
General Information: This genera consists of organisms typically found in the intestines of mammals, although through fecal contamination they can appear in sewage, soil, and water. They cause a number of infections that are becoming increasingly a problem due to the number of antibiotic resistance mechanisms these organisms have picked up. Both Enterococcus faecalis and Enterococcus faecium cause similar diseases in humans, and are mainly distinguished by their metabolic capabilities. This opportunistic pathogen can cause urinary tract infections, bacteremia (bacteria in the blood), and infective endocarditis (inflammation of the membrane surrounding the heart), similar to infections caused by Enterococcus faecium and faecalis. Hospital-acquired infections from this organism are on the rise due to the emergence of antiobiotic resistance strains.