Query: NC_013928:370893 Streptococcus mutans NN2025, complete genome
Lineage: Streptococcus mutans; Streptococcus; Streptococcaceae; Lactobacillales; Firmicutes; Bacteria
General Information: This strain is a clinical serotype c strain isolated in Japan in 2002. Streptococci are Gram-positive, nonmotile, nonsporeforming, catalase-negative cocci that occur in pairs or chains. Members of this genus vary widely in pathogenic potential. Most streptococci are facultative anaerobes, and some are obligate anaerobes. Streptococcus mutans was first isolated in 1924 from human carious (cavities) lesions and is the main cause of tooth decay. This organism thrives in a bacterial community known as a dental plaque which forms on the surface of teeth. This organism has also been implicated in cases of infective endocarditis.
Subject: NC_015052:1569255 Bifidobacterium longum subsp. infantis 157F, complete genome
Lineage: Bifidobacterium longum; Bifidobacterium; Bifidobacteriaceae; Bifidobacteriales; Actinobacteria; Bacteria
General Information: This organism is found in adult humans and formula fed infants as a normal component of gut flora. Representatives of this genus naturally colonize the human gastrointestinal tract (GIT) and are important for establishing and maintaining homeostasis of the intestinal ecosystem to allow for normal digestion. Their presence has been associated with beneficial health effects, such as prevention of diarrhea, amelioration of lactose intolerance, or immunomodulation. The stabilizing effect on GIT microflora is attributed to the capacity of bifidobacteria to produce bacteriocins, which are bacteriostatic agents with a broad spectrum of action, and to their pH-reducing activity.