Pre_GI: SWBIT SVG BLASTN

Query: NC_013887:1424000 Methanocaldococcus sp. FS406-22 chromosome, complete genome

Lineage: Methanocaldococcus; Methanocaldococcus; Methanocaldococcaceae; Methanococcales; Euryarchaeota; Archaea

General Information: Isolation: Deep-sea hydrothermal vent from Pacific; Temp: Thermophile; Temp: 90C; Habitat: Deep sea, Hydrothermal vent, Marine. Methanocaldococcus sp. FS406-22 was isolated from hydrothermal vent fluid from an undersea volcano in the northeast Pacific Ocean. This organism is able to fix nitrogen at temperatures of 92 degrees C.

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Subject: NC_004311:1096649 Brucella suis 1330 chromosome II, complete sequence

Lineage: Brucella suis; Brucella; Brucellaceae; Rhizobiales; Proteobacteria; Bacteria

General Information: A swine isolate. Causes brucellosis, infectious abortions, fevers. They are highly infectious, and can be spread through contact with infected animal products or through the air, making them a potential bioterrorism agent. Once the organism has entered the body, it can become intracellular, and enter the blood and lymphatic regions, multiplying inside phagocytes before eventually causing bacteremia (spread of bacteria through the blood). Virulence may depend on a type IV secretion system which may promote intracellular growth by secreting important effector molecules. This organism is a swine-specific Brucella. It causes infectious abortions in animals and a systemic, febrile (feverish) illness in humans. Brucella suis is considered a potential bioterrorism agent and was the first pathogenic organism to be weaponized by the USA.