Query: NC_013853:1295000 Streptococcus mitis B6, complete genome Lineage: Streptococcus mitis; Streptococcus; Streptococcaceae; Lactobacillales; Firmicutes; Bacteria General Information: This strain was isolated from a hospital in Bochum, Germany. Streptococcus mitis. This organism is a commensal normally found in the human mouth, throat and nasopharynx. It is not usually pathogenic but can be recovered from ulcerated teeth, sinuses and blood or heart lesions from subacute endocarditis (inflammation of the membrane lining the heart) patients. Streptococci are Gram-positive, nonmotile, nonsporeforming, catalase-negative cocci that occur in pairs or chains. Members of this genus vary widely in pathogenic potential. Most streptococci are facultative anaerobes, and some are obligate anaerobes.
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General Information: This strain is a hyper-virulent community acquired methicillin-susceptible (MSSA) strain isolated in the United Kingdom. Causes skin infections. Staphylcocci are generally found inhabiting the skin and mucous membranes of mammals and birds. Some members of this genus can be found as human commensals and these are generally believed to have the greatest pathogenic potential in opportunistic infections. This organism is a major cause of nosocomial (hospital-acquired) and community-acquired infections. Continues to be a major cause of mortality and is responsible for a variety of infections including, boils, furuncles, styes, impetigo and other superficial skin infections in humans. Also known to cause more serious infections particularly in the chronically ill or immunocompromised. The ability to cause invasive disease is associated with persistance in the nasal cavity of a host.