Query: NC_013522:1683326 Thermanaerovibrio acidaminovorans DSM 6589, complete genome Lineage: Thermanaerovibrio acidaminovorans; Thermanaerovibrio; Synergistaceae; Synergistales; Synergistetes; Bacteria General Information: Isolation: Upflow anaerobic sludge bed reactor of a sugar refinery in Netherlands; Country: Netherlands; Temp: Thermophile; Temp: 55C; Habitat: Sludge. A strictly anaerobic, motile, non-spore-forming, thermophilic Gram-negative bacterium. Thermanaerovibrio acidaminovorans formerly Selenomonas acidaminovorans, can be isolated from methanogenic sludge and is able to ferment amino acids and carbohydrates.
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General Information: Isolated from a patient with fever and lymphadenitis. Chronic granulomatous disease (CGD) is a rare inherited disease of the phagocyte NADPH oxidase system causing defective production of toxic oxygen metabolites, impaired bacterial and fungal killing, and recurrent life-threatening infections. This species was isolated from a 39 year old man with CGD and was shown to be the causal agent of the disease by classical methods. The isolation of this organism is the first known case of a bacterium from the Acetobacteraceae family to be the cause of an invasive human disease.