Pre_GI: SWBIT SVG BLASTN

Query: NC_013515:550464 Streptobacillus moniliformis DSM 12112, complete genome

Lineage: Streptobacillus moniliformis; Streptobacillus; Leptotrichiaceae; Fusobacteriales; Fusobacteria; Bacteria

General Information: Isolation: Patient with rat-bite fever in France; Temp: Mesophile; Temp: 37C; Habitat: Host. Streptobacillus moniliformis causes rat bite fever, a systemic illness characterized by fever, chills, and joint pain which can progress to endocarditis, meningitis or pneumonia if left untreated. Although infection is usually associated with a rodent bite, this disease can be caused by ingestion of contaminated food or water. Streptobacillus moniliformis is the causative agent of rat bite fever in North and South America while a different organism, Spirillum minus, is primarily responsible for this disease in Asia and other countries.

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Subject: NC_013316:81969 Clostridium difficile R20291, complete genome

Lineage: Peptoclostridium difficile; Peptoclostridium; Peptostreptococcaceae; Clostridiales; Firmicutes; Bacteria

General Information: Clostridium difficile R20291 was isolated in Stoke Mandeville Hospital, UK in 2006 and is closely related to the North American hypervirulent BI strains. Clostridium difficile, a Gram-positive, spore-forming anaerobic bacterium, is the leading cause of infectious diarrhea among patients in hospitals worldwide, causing C. difficile infection (CDI). An important nosocomial pathogen, it is frequently associated with antibiotic treatment and causes diseases ranging from antibiotic-associated diarrhea to life-threatening pseudomembraneous colitis.