Query: NC_013510:3065000 Thermomonospora curvata DSM 43183, complete genome
Lineage: Thermomonospora curvata; Thermomonospora; Thermomonosporaceae; Actinomycetales; Actinobacteria; Bacteria
General Information: Isolation: Municipal refuse compost samples; Temp: Thermophile; Temp: 65C. An aerobic, cellulolytic, thermophilic Gram-positive bacterium isolated from straw compost. Thermomonospora curvata is a thermophilic bacterium which produces a number of industrially important compounds like cellulase, alpha-amylase, and polygalacturonate lyase.
Subject: NC_008343:2589680 Granulibacter bethesdensis CGDNIH1, complete genome
Lineage: Granulibacter bethesdensis; Granulibacter; Acetobacteraceae; Rhodospirillales; Proteobacteria; Bacteria
General Information: Isolated from a patient with fever and lymphadenitis. Chronic granulomatous disease (CGD) is a rare inherited disease of the phagocyte NADPH oxidase system causing defective production of toxic oxygen metabolites, impaired bacterial and fungal killing, and recurrent life-threatening infections. This species was isolated from a 39 year old man with CGD and was shown to be the causal agent of the disease by classical methods. The isolation of this organism is the first known case of a bacterium from the Acetobacteraceae family to be the cause of an invasive human disease.