Query: NC_013508:1491945 Edwardsiella tarda EIB202, complete genome Lineage: Edwardsiella tarda; Edwardsiella; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria General Information: Edwardsiella tarda is a Gram-negative member of the normal gut microflora of fish, humans, chickens and other animals. This organism is also a serious pathogen of marine and freshwater fish and has been isolated from channel catfish, Japanese eels, flounder, tilapia, and other economically important fish. Infection by this organism is characterized by septicemia, internal abscesses, and skin lesions. This disease is often associated with poor water quality and mortality in aquaculture can be high. Edwardsiella tarda also causes opportunistic infections in humans, most commonly gastroenteritis and wound infections. However, this organism has been isolated from cases of septicemia and meningitis, primarily in immunocompromised patients.
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General Information: Edwardsiella ictaluri is the causative agent of enteric septicemia in catfish (ESC), an economically significant disease of farm-raised catfish. The acute form of ESC causes bacterial septicemia (proliferation of bacteria in the blood) which rapidly leads to death. The chronic form of this disease causes a characteristic head lesion, and may also proceed to septicemia and death. Two plasmids, which are consistently present in Edwardsiella ictaluri isolates, have been sequenced. Both plasmids contain genes for the type III secretory system, which is involved in translocating pathogenicity proteins into the eukaryotic cell.