Query: NC_013456:2984491 Vibrio sp. Ex25 chromosome 1, complete genome
Lineage: Vibrio; Vibrio; Vibrionaceae; Vibrionales; Proteobacteria; Bacteria
General Information: Vibrio sp. EX25 was isolated from samples taken from a deep-sea hydrothermal vent community along the East Pacific Rise. Vibrio species represent a significant portion of the culturable heterotrophic bacteria of oceans, coastal waters and estuaries. Various species of this genus are devastating pathogens for finfish, shellfish and mammals.
Subject: NC_009648:3224495 Klebsiella pneumoniae subsp. pneumoniae MGH 78578, complete genome
Lineage: Klebsiella pneumoniae; Klebsiella; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria
General Information: This strain was isolated from a patient in 1994. Opportunistic pathogen that causes multiple hospital-acquired infections. This organism is the most medically important organism within the genus Klebsiella. It is an environmental organism found in water, soil, and on the surface of plants. Several strains have been isolated from plant tissues and are nitrogen-fixing endophytes that may be a source of nitrogen for the plant. Other strains can become opportunistic pathogens which infect humans, and typically causes hospital-acquired infections in immunocompromised patients. Major sites of infection include the lungs, where it causes a type of pneumonia, and urinary tract infections. Klebsiella can also enter the bloodstream (bacterimia) and cause sepsis. The pathogen can also infect animals and cause inflammation of the uterus in horses as well as more generalized infections in other mammals. This organism expresses numerous pathogenicity factors, including multiple adhesins, capsular polysaccharide, siderophores, and lipopolysaccharide for the evasion of host defenses. The multiple antibiotic resistance genes carried on the chromosome inhibit efforts to clear the organism from infected patients via antibiotic use.