Pre_GI: SWBIT SVG BLASTN

Query: NC_013410:2586500 Fibrobacter succinogenes subsp. succinogenes S85 chromosome,

Lineage: Fibrobacter succinogenes; Fibrobacter; Fibrobacteraceae; Fibrobacterales; Fibrobacteres; Bacteria

General Information: Temp: Mesophile; Temp: 37C; Habitat: Host. Cellulolytic rumen bacterium. This bacterium is one of the three most predominant cellulolytic organisms in the rumen. Since cellulose is one of the most abundant carbohydrates on the planet, this organism is, therefore, an important part of the global carbon biogeochemical cycle, converting the mass of fixed carbon generated by photosynthetic organisms back to products that eventually end up as carbon dioxide. Increasing cellulose degradation is an important goal in industrial processes. This organism is highly specialized for cellulose degradation, and is only capable of utilizing cellulose and cellulolytic degradation products as carbon sources. Access to cellulose is a rate-liming step in degradation, and the cellulolytic organisms have devised a number of mechanisms for improving access to this insoluble substrate, one of which is the production of surface-localized cellulases. The active enzymes are cell wall associated, but the presence of cellulosomes, large multiprotein cellulase complexes, has not been detected in this organism. Adherence is another method used to promote cellulose degradation, and this organism produces an extracellular matrix of glycoprotein glycocalyx which allows attachment to insoluble cellulose.

Subject: NC_010159:2128157 Yersinia pestis Angola, complete genome

Lineage: Yersinia pestis; Yersinia; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: This strain was isolated prior to 1985 and belongs to the antiqua biovar. It can ferment rhamnonse and melibiose which is a property usually associated with Yersinia pseudotuberculosis. Strain Angola belongs to a group of atypical Yersinia pestis strains with genotypic similarities that are intermediate between Y. pestis and Y. pseudotuberuclosis strains. Genotypic studies indicate that strain Angola is the oldest Y. pestis strain analyzed to date. It carries three plasmids that are similar to other Y. pestis plasmids but have aberrant sizes. The critical virulence factor, the V antigen, is different than that encoded by typical strains of Y. pestis and there is a deletion that affects the F1 operon. Strain Angola has been shown to be virulent by aerosol in mice.