Pre_GI: SWBIT SVG BLASTN

Query: NC_013410:155236 Fibrobacter succinogenes subsp. succinogenes S85 chromosome,

Lineage: Fibrobacter succinogenes; Fibrobacter; Fibrobacteraceae; Fibrobacterales; Fibrobacteres; Bacteria

General Information: Temp: Mesophile; Temp: 37C; Habitat: Host. Cellulolytic rumen bacterium. This bacterium is one of the three most predominant cellulolytic organisms in the rumen. Since cellulose is one of the most abundant carbohydrates on the planet, this organism is, therefore, an important part of the global carbon biogeochemical cycle, converting the mass of fixed carbon generated by photosynthetic organisms back to products that eventually end up as carbon dioxide. Increasing cellulose degradation is an important goal in industrial processes. This organism is highly specialized for cellulose degradation, and is only capable of utilizing cellulose and cellulolytic degradation products as carbon sources. Access to cellulose is a rate-liming step in degradation, and the cellulolytic organisms have devised a number of mechanisms for improving access to this insoluble substrate, one of which is the production of surface-localized cellulases. The active enzymes are cell wall associated, but the presence of cellulosomes, large multiprotein cellulase complexes, has not been detected in this organism. Adherence is another method used to promote cellulose degradation, and this organism produces an extracellular matrix of glycoprotein glycocalyx which allows attachment to insoluble cellulose.

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BLASTN Alignment.txt

Subject: NC_012778:1946924 Eubacterium eligens ATCC 27750, complete genome

Lineage: Eubacterium eligens; Eubacterium; Eubacteriaceae; Clostridiales; Firmicutes; Bacteria

General Information: Eubacterium eligens ATCC 27750 is part of the normal human gut flora. This genus has been isolated as normal flora from feces, rumen, and periodontal tissue. Eubacterium spp. are thought to play a beneficial role in maintaining the normal ecology of the large intestine, in part by producing chemicals like butyric acid which act to inhibit the growth of other bacteria. These organisms are occasionally isolated from wounds and abscesses and may be an opportunistic pathogen. This genus has also been isolated from sewage and soil.