Query: NC_013385:1504650 Ammonifex degensii KC4, complete genome
Lineage: Ammonifex degensii; Ammonifex; Thermoanaerobacteraceae; Thermoanaerobacterales; Firmicutes; Bacteria
General Information: Isolation: Neutral volcanic hot spring; Temp: Thermophile; Temp: 70C; Habitat: Fresh water, Hot spring. This organism is a thermophilic chemoautotroph able to grow by nitrate ammonification or by sulfate and sulfur reduction. It was isolated from a neutral volcanic hot spring.
Subject: NC_003116:93576 Neisseria meningitidis Z2491, complete genome
Lineage: Neisseria meningitidis; Neisseria; Neisseriaceae; Neisseriales; Proteobacteria; Bacteria
General Information: This is a serogroup A strain isolated in Gambia in 1983. Causes septicemia and meningitis. The second of two pathogenic Neisseria, this organism causes septicemia and is the leading cause of life-threatening meningitis (inflammation of the meninges, the membrane surrounding the brain and spinal cord) in children. This organism typically residies in the nasopharynx cavity but can invade the respiratory epthelial barrier, cross into the bloodstream and the blood brain barrier, and cause inflammation of the meninges. Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). This organism, like Neisseria gonorrhoeae, is naturally competent, and protein complexes at the cell surface recognize the uptake signal sequence in extracellular DNA, an 8mer that is found at high frequency in Neisseria chromosomal DNA.