Query: NC_013316:3056925 Clostridium difficile R20291, complete genome
Lineage: Peptoclostridium difficile; Peptoclostridium; Peptostreptococcaceae; Clostridiales; Firmicutes; Bacteria
General Information: Clostridium difficile R20291 was isolated in Stoke Mandeville Hospital, UK in 2006 and is closely related to the North American hypervirulent BI strains. Clostridium difficile, a Gram-positive, spore-forming anaerobic bacterium, is the leading cause of infectious diarrhea among patients in hospitals worldwide, causing C. difficile infection (CDI). An important nosocomial pathogen, it is frequently associated with antibiotic treatment and causes diseases ranging from antibiotic-associated diarrhea to life-threatening pseudomembraneous colitis.
Subject: NC_014974:404015 Thermus scotoductus SA-01 chromosome, complete genome
Lineage: Thermus scotoductus; Thermus; Thermaceae; Thermales; Deinococcus-Thermus; Bacteria
General Information: This is a thermophilic, facultatively mixotrophic sulfur-oxidizing bacterium. Thermus scotoductus SA-01 was isolated from fissure water in a South African gold mine. This organism is a thermophilic bacterium which was isolated from fissure water in the Witwatersrand Supergroup at a depth of 3.2 km below surface in a South African gold mine. It is a 2.9-billion-year-old formation of low permeability sandstone and shale with minor volcanic units and conglomerates. The ambient temperature of the rock is approximately 60°C. Samples were collected from a freshly mined rock surface and from a water-producing borehole that penetrated 121 m horizontally into the formation at a depth of 3,198 m. T. scotoductus SA-01 is a facultative anaerobe capable of coupling the oxidation of organic substrates to reduction of a wide range of electron acceptors, including nitrate, Fe(III), Mn(IV) or S(0) as terminal electron acceptors.