Pre_GI: SWBIT SVG BLASTN

Query: NC_013192:1941002 Leptotrichia buccalis DSM 1135, complete genome

Lineage: Leptotrichia buccalis; Leptotrichia; Leptotrichiaceae; Fusobacteriales; Fusobacteria; Bacteria

General Information: Temp: Mesophile; Temp: 37C; Habitat: Blood, Human oral microflora. Leptotrichia buccalis DSM 1135 was isolated from dental plaque. This organism is a member of the normal human oral microbial community but has occasionally been implicated in cases of septicemia and endocarditis.

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BLASTN Alignment.txt

Subject: NC_004311:1096649 Brucella suis 1330 chromosome II, complete sequence

Lineage: Brucella suis; Brucella; Brucellaceae; Rhizobiales; Proteobacteria; Bacteria

General Information: A swine isolate. Causes brucellosis, infectious abortions, fevers. They are highly infectious, and can be spread through contact with infected animal products or through the air, making them a potential bioterrorism agent. Once the organism has entered the body, it can become intracellular, and enter the blood and lymphatic regions, multiplying inside phagocytes before eventually causing bacteremia (spread of bacteria through the blood). Virulence may depend on a type IV secretion system which may promote intracellular growth by secreting important effector molecules. This organism is a swine-specific Brucella. It causes infectious abortions in animals and a systemic, febrile (feverish) illness in humans. Brucella suis is considered a potential bioterrorism agent and was the first pathogenic organism to be weaponized by the USA.