Query: NC_013174:601434 Jonesia denitrificans DSM 20603, complete genome Lineage: Jonesia denitrificans; Jonesia; Jonesiaceae; Actinomycetales; Actinobacteria; Bacteria General Information: Isolation: Boiled ox blood; Temp: Mesophile; Temp: 37C. This species was formerly classified as Listeria denitrificans, and is the only species of the genus Jonesia. It is a Gram-positive nonspore-forming, motile rod that is catalase positive, oxidase negative, and facultatively anaerobic.
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General Information: Sorangium cellulosum 'So ce 56' produces a large number of bioactive compounds, such as, the antifungal soraphen and the anticancer agent epothilone. This organism, like other myxobacteria, undergoes a complex development and differentiation pathway. When cell density increases, the organism switches to "social motility" where aggregates of cells can gather together into masses termed fruiting bodies that may consist of up to 100 000 cells. The motility system is not dependent on flagella like most bacteria, but instead relies on twitching pili: short extracellular appendages that may function analogously to oars in a rowboat. The myxobacteria have proved to be a rich source of novel natural products. Sorangium cellulosum produces a number of antibacterial, antifungal and cytotoxic substances which are being studies for therapeutic applications.