Query: NC_013170:277321 Cryptobacterium curtum DSM 15641, complete genome
Lineage: Cryptobacterium curtum; Cryptobacterium; Coriobacteriaceae; Coriobacteriales; Actinobacteria; Bacteria
General Information: Isolation: Periodontal pocket of an adult patient; Temp: Mesophile; Temp: 37C; Habitat: Host, Human oral microflora. This organism has been isolated from periodontal lesions and may play an important role in those infections.
Subject: NC_008343:2589680 Granulibacter bethesdensis CGDNIH1, complete genome
Lineage: Granulibacter bethesdensis; Granulibacter; Acetobacteraceae; Rhodospirillales; Proteobacteria; Bacteria
General Information: Isolated from a patient with fever and lymphadenitis. Chronic granulomatous disease (CGD) is a rare inherited disease of the phagocyte NADPH oxidase system causing defective production of toxic oxygen metabolites, impaired bacterial and fungal killing, and recurrent life-threatening infections. This species was isolated from a 39 year old man with CGD and was shown to be the causal agent of the disease by classical methods. The isolation of this organism is the first known case of a bacterium from the Acetobacteraceae family to be the cause of an invasive human disease.