Query: NC_013119:1932402 Brucella microti CCM 4915 chromosome 1, complete sequence Lineage: Brucella microti; Brucella; Brucellaceae; Rhizobiales; Proteobacteria; Bacteria General Information: Brucella microti was isolated in 2000 from systemically infected voles in South Moravia, Czech Republic and has been more recently isolated from foxes and apparently free-living in soil in Czech soil. The organism is characterized by rapid growth on standard media and high metabolic activity, which is atypical for Brucella.
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General Information: Causes bovine brucellosis. They are highly infectious, and can be spread through contact with infected animal products or through the air, making them a potential bioterrorism agent. Once the organism has entered the body, it can become intracellular, and enter the blood and lymphatic regions, multiplying inside phagocytes before eventually causing bacteremia (spread of bacteria through the blood). Once the organism has entered the body, it can become intracellular, and enter the blood and lymphatic regions, multiplying inside phagocytes before eventually causing bacteremia (spread of bacteria through the blood). Virulence may depend on a type IV secretion system which may promote intracellular growth by secreting important effector molecules. This organism was first noticed on the island of Malta. It is the primary cause of bovine brucellosis, which results in enormous (billions of dollars) economic losses due primarily to reproductive failure and food losses. In man, it causes undulant fever, a long debilitating disease that is treated by protracted administration of antibiotics.