Query: NC_013118:1109610 Brucella microti CCM 4915 chromosome 2, complete genome Lineage: Brucella microti; Brucella; Brucellaceae; Rhizobiales; Proteobacteria; Bacteria General Information: Brucella microti was isolated in 2000 from systemically infected voles in South Moravia, Czech Republic and has been more recently isolated from foxes and apparently free-living in soil in Czech soil. The organism is characterized by rapid growth on standard media and high metabolic activity, which is atypical for Brucella.
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General Information: Isolated from a patient with fever and lymphadenitis. Chronic granulomatous disease (CGD) is a rare inherited disease of the phagocyte NADPH oxidase system causing defective production of toxic oxygen metabolites, impaired bacterial and fungal killing, and recurrent life-threatening infections. This species was isolated from a 39 year old man with CGD and was shown to be the causal agent of the disease by classical methods. The isolation of this organism is the first known case of a bacterium from the Acetobacteraceae family to be the cause of an invasive human disease.