Pre_GI: SWBIT SVG BLASTN

Query: NC_013093:5419458 Actinosynnema mirum DSM 43827, complete genome

Lineage: Actinosynnema mirum; Actinosynnema; Pseudonocardiaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: Isolation: Blade of grass from Raritan River NJ; Country: USA; Temp: Mesophile; Temp: 10-30C; Habitat: Soil. This bacterium produces the antibiotic nocardicin A. Soil dwelling, nonmotile aerobe it has fine hyphae which form aerial and substrate mycelia. Motile spores are borne on synnemata, compact groups of erect hyphae. It produces nocardicin antibiotics and is able to inhibit growth of several Gram-positive bacteria as well as some filamentous fungi and yeasts.

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BLASTN Alignment.txt

Subject: NC_002944:1285436 Mycobacterium avium subsp. paratuberculosis K-10, complete genome

Lineage: Mycobacterium avium; Mycobacterium; Mycobacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: This strain was isolated from a diary herd in Wisconsin, USA in the 1970's. Environmental organism which causes infections in birds and humans. This genus comprises a number of Gram-positive, acid-fast, rod-shaped aerobic bacteria and is the only member of the family Mycobacteriaceae within the order Actinomycetales. Like other closely related Actinomycetales, such as Nocardia and Corynebacterium, Mycobacteria have unusually high genomic DNA GC content and are capable of producing mycolic acids as major components of their cell wall. Mycobacterium avium is ubiquitous in the environment, and can be found in stagnant waters and soils. This organism causes tuberculosis in birds and disseminated infections in immunocompromized humans (the elderly, children, and especially patients with AIDS). Infection results in a characteristic pulmonary disease which requires expensive drug therapy for successful treatment. Most prevalent colony morphotypes are smooth opaque, smooth transparent and rough, with the last two being the faster growers in vivo.