Pre_GI: SWBIT SVG BLASTN

Query: NC_012917:569856 Pectobacterium carotovorum subsp. carotovorum PC1, complete genome

Lineage: Pectobacterium carotovorum; Pectobacterium; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: Temp: Mesophile; Habitat: Host. Pectobacterium carotovorum causes soft-rot diseases of various plant hosts through degradation of the plant cell walls. Formerly Erwinia, these organisms are plant-specific pathogens that invade the vascular systems of plants. Pectobacterium colonize the intercellular spaces of plant cells and deliver potent effector molecules (Avr - avirulence) through a type III secretion system (Hrp - hypersensitive response and pathogenicity). Avr proteins control host-bacterium interactions, including host range. Expression of the plant cell-wall-degrading enzymes is controlled through a quorum-sensing mechanism that quantifies the number of Pectobacterium bacteria through measurement of the concentration of small molecules (acyl homoserine lactones) produced by Pectobacterium.

Subject: NC_010554:2789722 Proteus mirabilis HI4320, complete genome

Lineage: Proteus mirabilis; Proteus; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: Proteus mirabilis is a tetracycline resistant human urinary tract isolate. This bacterium is part of the normal gut flora of a healthy individual, but is also an opportunistic pathogen. Flagellar movement allows this organism to travel through the urinary tract into the bladder and kidney where it may cause infection or stones. Cell death is caused by hemolysin, a pore-forming toxin which disrupts osmotic balance across the host cell membrane. This species is inherently resistant to nitrofuran and tetracycline, and some strains have recently become resistant to ampicillin and trimethoprin.