Query: NC_012913:1041969 Aggregatibacter aphrophilus NJ8700, complete genome
Lineage: Aggregatibacter aphrophilus; Aggregatibacter; Pasteurellaceae; Pasteurellales; Proteobacteria; Bacteria
General Information: Aggregatibacter aphrophilus (formerly Haemophilus aphrophilus) is an etiologic agent in infectious endocarditis caused by gram-negative bacteria. It is often found as a nonpathogenic, commensal resident of dental plaque and the oropharyngeal flora.
Subject: NC_013416:820989 Aggregatibacter actinomycetemcomitans D11S-1, complete genome
Lineage: Aggregatibacter actinomycetemcomitans; Aggregatibacter; Pasteurellaceae; Pasteurellales; Proteobacteria; Bacteria
General Information: Aggregatibacter actinomycetemcomitans D11S-1 was recovered from a subject with aggressive periodontitis. Aggregatibacter actinomycetemcomitans, previously Actinobacillus actinomycetemcomitans typically resides in the oral cavity of humans and animals and can cause a number of diseases. The bacterium, along with 3 other organisms, is the main culprit in periodontis, which results in devastation to the bone supporting the teeth. Adherence to oral surfaces is controlled through the tad (tight adherence) locus, which may express proteins that are involved in type IV secretion.