Pre_GI: SWBIT SVG BLASTN

Query: NC_012883:104987 Thermococcus sibiricus MM 739, complete genome

Lineage: Thermococcus sibiricus; Thermococcus; Thermococcaceae; Thermococcales; Euryarchaeota; Archaea

General Information: Thermococcus sibiricus is a hyperthermophilic anaerobic archaeon isolated from a well of the never flooded oil-bearing Jurassic horizon of the high-temperature Samotlor oil reservoir (Western Siberia). The organism is indigenous to the reservoir and survived over geologic time by metabolizing buried organic matter from the original oceanic sediment.

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Subject: NC_018870:1417851 Thermacetogenium phaeum DSM 12270 chromosome, complete genome

Lineage: Thermacetogenium phaeum; Thermacetogenium; Thermoanaerobacteraceae; Thermoanaerobacterales; Firmicutes; Bacteria

General Information: Nitrogen fixation. Thermophilic strictly anaerobic bacterium oxidizing acetate to CO2 in syntrophic association with a methanogenic partner. Capable of growing with various substrates such as alcohols and methylated nitrogen compounds, and to reduce sulfate in the presence of acetate. Isolated from sludge of an anaerobic digester run at 58 degrees C. Thermacetogenium phaeum is a strictly anaerobic, homoacetogenic bacterium. It is exceptional because it can use the homoacetogenic Wood-Ljungdahl (CO- dehydrogenase) pathway both for acetate formation and acetate oxidation. Acetate oxidation is possible only in syntrophic cooperation with a methanogenic partner which maintains a low hydrogen and/or formate concentration in the coculture. With this, the bacterium operates close to the thermodynamic equilibrium of substrate conversion, similar to other syntrophically fermenting bacteria such as Syntrophomonas wolfei the genomes of which have been sequenced as well in the recent past.