Query: NC_012856:1080000 Ralstonia pickettii 12D chromosome 1, complete genome Lineage: Ralstonia pickettii; Ralstonia; Burkholderiaceae; Burkholderiales; Proteobacteria; Bacteria General Information: Isolation: Copper-contaminated sediment from a lake; Country: USA; Temp: Mesophile; Habitat: Fresh water, Host, Soil. Ralstonia pickettii can be isolated from a wide range of environmental and clinical samples. This species is a nocosomial pathogen. It is associated with infections caused by contaminated solutions, such as distilled water and intravenous solutions. Ralstonia pickettii strains resistant to heavy metals have also been isolated from heavy metal contaminated environments.
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General Information: First isolated in 1960 in Oxford, England, as an airborne contaminant growing on methylamine. This strain can grow on methylamine or methanol, but not methane. This organism is capable of growth on one-carbon compounds such as methanol. Methanol is oxidized to formaldehyde which is then used metabolically to generate either energy or biomass. These bacteria are commonly found in the environment, especially associated with plants which produce methanol when metabolizing pectin during cell wall synthesis. At least 25 genes are required for this complex process of converting methanol to formaldehyde and this specialized metabolic pathway is of great interest.