Query: NC_012808:420334 Methylobacterium extorquens AM1, complete genome Lineage: Methylobacterium extorquens; Methylobacterium; Methylobacteriaceae; Rhizobiales; Proteobacteria; Bacteria General Information: First isolated in 1960 in Oxford, England, as an airborne contaminant growing on methylamine. This strain can grow on methylamine or methanol, but not methane. This organism is capable of growth on one-carbon compounds such as methanol. Methanol is oxidized to formaldehyde which is then used metabolically to generate either energy or biomass. These bacteria are commonly found in the environment, especially associated with plants which produce methanol when metabolizing pectin during cell wall synthesis. At least 25 genes are required for this complex process of converting methanol to formaldehyde and this specialized metabolic pathway is of great interest.
- Sequence; - BLASTN hit (Low score = Light, High score = Dark) - hypothetical protein; - cds: hover for description
General Information: Enterobacter species are found in natural environments such as water, sewage, soil, and vegetables; some species are found in human and animal species. Enterobacter cloacae is a prevalent nosocomial pathogen as it is highly resistant to disinfectants and antimicrobial agents. E.cloacae subsp. cloacae strain ATCC 13047 was isolated from human cerebrospinal fluid in 1890 and is the type strain. These "ICU bugs" cause significant morbidity and mortality, and infection management is complicated by multiple antibiotic resistance. These bacteria possess inducible beta-lactamases, which are undetectable in vitro but are also responsible for resistance during treatment.