Pre_GI: SWBIT SVG BLASTN

Query: NC_012808:806432 Methylobacterium extorquens AM1, complete genome

Lineage: Methylobacterium extorquens; Methylobacterium; Methylobacteriaceae; Rhizobiales; Proteobacteria; Bacteria

General Information: First isolated in 1960 in Oxford, England, as an airborne contaminant growing on methylamine. This strain can grow on methylamine or methanol, but not methane. This organism is capable of growth on one-carbon compounds such as methanol. Methanol is oxidized to formaldehyde which is then used metabolically to generate either energy or biomass. These bacteria are commonly found in the environment, especially associated with plants which produce methanol when metabolizing pectin during cell wall synthesis. At least 25 genes are required for this complex process of converting methanol to formaldehyde and this specialized metabolic pathway is of great interest.

Subject: NC_005295:647275 Ehrlichia ruminantium str. Welgevonden, complete genome

Lineage: Ehrlichia ruminantium; Ehrlichia; Anaplasmataceae; Rickettsiales; Proteobacteria; Bacteria

General Information: This strain was isolated in mice from an infected tick. Obligate intracellular bacterium and causative agent of heartwater. This organism causes heartwater, a disease with a high mortality rate that affects both wild and domesticated ruminants in sub-Saharan Africa and parts of the Caribbean. The name heartwater refers to the hydropericardium (excessive fluid in the sac surrounding the heart) commonly found associated with infection. This organism is found in membrane-bound vacuoles in endothelial cells and neutrophils and is an obligate intracellular parasite.