Query: NC_012779:610509 Edwardsiella ictaluri 93-146, complete genome Lineage: Edwardsiella ictaluri; Edwardsiella; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria General Information: Edwardsiella ictaluri is the causative agent of enteric septicemia in catfish (ESC), an economically significant disease of farm-raised catfish. The acute form of ESC causes bacterial septicemia (proliferation of bacteria in the blood) which rapidly leads to death. The chronic form of this disease causes a characteristic head lesion, and may also proceed to septicemia and death. Two plasmids, which are consistently present in Edwardsiella ictaluri isolates, have been sequenced. Both plasmids contain genes for the type III secretory system, which is involved in translocating pathogenicity proteins into the eukaryotic cell.
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General Information: This organism is found in adult humans and formula fed infants as a normal component of gut flora. Representatives of this genus naturally colonize the human gastrointestinal tract (GIT) and are important for establishing and maintaining homeostasis of the intestinal ecosystem to allow for normal digestion. Their presence has been associated with beneficial health effects, such as prevention of diarrhea, amelioration of lactose intolerance, or immunomodulation. The stabilizing effect on GIT microflora is attributed to the capacity of bifidobacteria to produce bacteriocins, which are bacteriostatic agents with a broad spectrum of action, and to their pH-reducing activity.