Query: NC_012751:899394 Candidatus Hamiltonella defensa 5AT (Acyrthosiphon pisum), complete Lineage: Hamiltonella defensa; Hamiltonella; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria General Information: Candidatus Hamiltonella defensa 5AT was isolated from the pea aphid Acyrthosiphon pisum. Candidatus Hamiltonella defensa is a secondary endosymbiont of aphids. This organism protects the aphid host by killing parasitic wasp larvae.
- Sequence; - BLASTN hit (Low score = Light, High score = Dark) - hypothetical protein; - cds: hover for description
General Information: This strain was isolated from stool samples from an outbreak that involved three individuals in Nebraska, USA 1996. This organism is a soil-dwelling opportunistic pathogen that causes food poisoning in infected individuals. The rapid onset is characterized by nausea and vomiting while the late onset is characterized by diarrhea and abdominal pain. The emetic disease is caused by a small stable dodecadepsipeptide cerulide whereas the diarrheal disease is caused by a heat labile enterotoxin. Some strains produce a potent cytotoxin that forms a pore in the membrane of eukaryotic cells and causes necrotic enteritis (death of intestinal epithelial cells) while the unique tripartite membrane lytic toxin hemolysin BL contributes to the diarrheal disease and destructive infections of the eye.