Pre_GI: SWBIT SVG BLASTN

Query: NC_012731:600518 Klebsiella pneumoniae NTUH-K2044 chromosome, complete genome

Lineage: Klebsiella pneumoniae; Klebsiella; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: This strain was isolated from a liver abscess. This organism is the most medically important organism within the genus Klebsiella. It is an environmental organism found in water, soil, and on the surface of plants. Several strains have been isolated from plant tissues and are nitrogen-fixing endophytes that may be a source of nitrogen for the plant. Other strains can become opportunistic pathogens which infect humans, and typically causes hospital-acquired infections in immunocompromised patients. Major sites of infection include the lungs, where it causes a type of pneumonia, and urinary tract infections. Klebsiella can also enter the bloodstream (bacterimia) and cause sepsis. The pathogen can also infect animals and cause inflammation of the uterus in horses as well as more generalized infections in other mammals. This organism expresses numerous pathogenicity factors, including multiple adhesins, capsular polysaccharide, siderophores, and lipopolysaccharide for the evasion of host defenses. The multiple antibiotic resistance genes carried on the chromosome inhibit efforts to clear the organism from infected patients via antibiotic use.

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BLASTN Alignment.txt

Subject: NC_011901:2983555 Thioalkalivibrio sulfidophilus HL-EbGr7 chromosome, complete

Lineage: Thioalkalivibrio sulfidophilus; Thioalkalivibrio; Ectothiorhodospiraceae; Chromatiales; Proteobacteria; Bacteria

General Information: Obligately chemolithoautotrophic, haloalkaliphilic, mesophilic, microaerophilic and sulfur-oxidizing bacterium. Uses CO2 as a carbon source and reduced inorganic sulfur compounds as an energy source. Utilizes ammonium and urea, but not nitrate or nitrite, as a N-source. Isolated from a full-scale Thiopaq bioreactor in the Netherlands used to remove H2S from biogas. Thioalkalivibrio species are commonly isolated from soda lakes and tend to dominate the microbial community of hypersaline soda lakes. These organisms have a pH optimum of 10 and are able to oxidize hydrogen sulfide to elemental sulfur. Thioalkalivibrio species have also been isolated from sulfide oxidizing bioreactors which remove sulfide from refinery and natural gas.