Pre_GI: SWBIT SVG BLASTN

Query: NC_012731:600518 Klebsiella pneumoniae NTUH-K2044 chromosome, complete genome

Lineage: Klebsiella pneumoniae; Klebsiella; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: This strain was isolated from a liver abscess. This organism is the most medically important organism within the genus Klebsiella. It is an environmental organism found in water, soil, and on the surface of plants. Several strains have been isolated from plant tissues and are nitrogen-fixing endophytes that may be a source of nitrogen for the plant. Other strains can become opportunistic pathogens which infect humans, and typically causes hospital-acquired infections in immunocompromised patients. Major sites of infection include the lungs, where it causes a type of pneumonia, and urinary tract infections. Klebsiella can also enter the bloodstream (bacterimia) and cause sepsis. The pathogen can also infect animals and cause inflammation of the uterus in horses as well as more generalized infections in other mammals. This organism expresses numerous pathogenicity factors, including multiple adhesins, capsular polysaccharide, siderophores, and lipopolysaccharide for the evasion of host defenses. The multiple antibiotic resistance genes carried on the chromosome inhibit efforts to clear the organism from infected patients via antibiotic use.

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BLASTN Alignment.txt

Subject: NC_009138:1974935 Herminiimonas arsenicoxydans, complete genome

Lineage: Herminiimonas arsenicoxydans; Herminiimonas; Oxalobacteraceae; Burkholderiales; Proteobacteria; Bacteria

General Information: Herminiimonas arsenicoxydans was isolated from heavy metal contaminated sludge from an industrial water treatment plant. This organism has a number of mechanisms for metabolizing arsenic allowing it to effectively colonize arsenic-contaminated environments. A bacterium capable of oxidizing and reducing arsenic. This heterotrophic bacterium is capable of reducing and oxidizing arsenic with the objective of detoxification. Arsenic is both a product from natural sources and of human activities, and is widely distributed in the environment, essentially in 3 different oxidation states: As (-III) (arsine), As (+III) (arsenite) and As (+V) (arseniate). The ecology of this metalloid is strongly dependent on microbial transformations which affect the mobility and bioavailability as well as the toxicity of arsenic in the environment.