Pre_GI: SWBIT SVG BLASTN

Query: NC_012668:62500 Vibrio cholerae MJ-1236 chromosome 1, complete sequence

Lineage: Vibrio cholerae; Vibrio; Vibrionaceae; Vibrionales; Proteobacteria; Bacteria

General Information: Vibrio cholerae MJ-1236 is a toxigenic O1 El Tor Inaba strain from Matlab, Bangladesh, 1994 that represents the "Matlab variant" of El Tor. This genus is abundant in marine or freshwater environments such as estuaries, brackish ponds, or coastal areas; regions that provide an important reservoir for the organism in between outbreaks of the disease. Vibrio can affect shellfish, finfish, and other marine animals and a number of species are pathogenic for humans. Vibrio cholerae can colonize the mucosal surface of the small intestines of humans where it will cause cholera, a severe and sudden onset diarrheal disease. One famous outbreak was traced to a contaminated well in London in 1854 by John Snow, and epidemics, which can occur with extreme rapidity, are often associated with conditions of poor sanitation. The disease has a high lethality if left untreated, and millions have died over the centuries. There have been seven major pandemics between 1817 and today. Six were attributed to the classical biotype, while the 7th, which started in 1961, is associated with the El Tor biotype.

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BLASTN Alignment.txt

Subject: NC_014733:2363838 Methylovorus sp. MP688 chromosome, complete genome

Lineage: Methylovorus; Methylovorus; Methylophilaceae; Methylophilales; Proteobacteria; Bacteria

General Information: Methylotrophic bacteria are a group of bacteria which are able to grow aerobically at the expense of methanol as the sole source of carbon and energy, and therefore could serve as biocatalysts for the conversion of methanol to commercially valuable multicarbon compounds like amino acids and cytochromes. Pink-pigmented facultative methylotrophs of the genus Methylovorus are ubiquitous in soil, air and water environments. The MP688 strain was isolated from soil as an PQQ producer.