Query: NC_012668:1036000 Vibrio cholerae MJ-1236 chromosome 1, complete sequence

Lineage: Vibrio cholerae; Vibrio; Vibrionaceae; Vibrionales; Proteobacteria; Bacteria

General Information: Vibrio cholerae MJ-1236 is a toxigenic O1 El Tor Inaba strain from Matlab, Bangladesh, 1994 that represents the "Matlab variant" of El Tor. This genus is abundant in marine or freshwater environments such as estuaries, brackish ponds, or coastal areas; regions that provide an important reservoir for the organism in between outbreaks of the disease. Vibrio can affect shellfish, finfish, and other marine animals and a number of species are pathogenic for humans. Vibrio cholerae can colonize the mucosal surface of the small intestines of humans where it will cause cholera, a severe and sudden onset diarrheal disease. One famous outbreak was traced to a contaminated well in London in 1854 by John Snow, and epidemics, which can occur with extreme rapidity, are often associated with conditions of poor sanitation. The disease has a high lethality if left untreated, and millions have died over the centuries. There have been seven major pandemics between 1817 and today. Six were attributed to the classical biotype, while the 7th, which started in 1961, is associated with the El Tor biotype.

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BLASTN Alignment.txt

Subject: NC_007947:797456 Methylobacillus flagellatus KT, complete genome

Lineage: Methylobacillus flagellatus; Methylobacillus; Methylophilaceae; Methylophilales; Proteobacteria; Bacteria

General Information: This strain was isolated from activated sludge found at the wastewater treatment plant in Moscow, Russia and is the fastest growing methylotroph discovered. Methanol-degrading bacterium. Methylobacillus flagellatus is a methylotroph, able to grow on compounds such as methanol and methyamines. These organisms play a role in the environmental cycling of carbon and nitrogen.