Query: NC_012590:1446500 Corynebacterium aurimucosum ATCC 700975, complete genome
Lineage: Corynebacterium aurimucosum; Corynebacterium; Corynebacteriaceae; Actinomycetales; Actinobacteria; Bacteria
General Information: Corynebacterium aurimucosum ATCC 700975 (DSM 44827) was isolated from the human female urogenital tract. Corynebacterium aurimucosum has been isolated from a number of clinical samples including blood and infected bone, however it is not known what role this organism may have in the development of disease. This organism is also isolated from healthy female urogenital tract samples and is considered part of the normal microbial community.
Subject: NC_008611:3579500 Mycobacterium ulcerans Agy99, complete genome
Lineage: Mycobacterium ulcerans; Mycobacterium; Mycobacteriaceae; Actinomycetales; Actinobacteria; Bacteria
General Information: This organism causes Buruli ulcer and is the third most common mycobacterial pathogen after Mycobacterium tuberculosis and Mycobacterium leprae. The disease has increased dramatically through central and West Africa since the late 1980s. Causative agent of Buruli and Bairnsdale ulcer. Infection by Mycobacterium ulcerans causes the formation of skin ulcers which, if left untreated, can lead to extensive scarring and/or amputation. Mycobacterium ulcerans produces a cytotoxin, mycolactone, which causes the destruction of skin tissue seen in this disease. This organism is resistant to antibiotics and treatment involves the surgical removal of infected tissues.