Query: NC_012491:3115518 Brevibacillus brevis NBRC 100599, complete genome
Lineage: Brevibacillus brevis; Brevibacillus; Paenibacillaceae; Bacillales; Firmicutes; Bacteria
General Information: Strictly aerobic, Gram-positive, spore-forming soil bacterium. When faced with nutritional stress, this species develops genetic competance and motility, sporulates, and produces antibiotics during the transition between the exponential and stationary phases. The genes involved in antibiotic production have been well characterized and have led to the commercial production of tyrocidine and gramicidin.
Subject: NC_011772:2305000 Bacillus cereus G9842, complete genome
Lineage: Bacillus cereus; Bacillus; Bacillaceae; Bacillales; Firmicutes; Bacteria
General Information: This strain was isolated from stool samples from an outbreak that involved three individuals in Nebraska, USA 1996. This organism is a soil-dwelling opportunistic pathogen that causes food poisoning in infected individuals. The rapid onset is characterized by nausea and vomiting while the late onset is characterized by diarrhea and abdominal pain. The emetic disease is caused by a small stable dodecadepsipeptide cerulide whereas the diarrheal disease is caused by a heat labile enterotoxin. Some strains produce a potent cytotoxin that forms a pore in the membrane of eukaryotic cells and causes necrotic enteritis (death of intestinal epithelial cells) while the unique tripartite membrane lytic toxin hemolysin BL contributes to the diarrheal disease and destructive infections of the eye.