Pre_GI: SWBIT SVG BLASTN

Query: NC_012207:477500 Mycobacterium bovis BCG str. Tokyo 172, complete genome

Lineage: Mycobacterium bovis; Mycobacterium; Mycobacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: Used for the production of BCG vaccine in Japan. Causative agent of classic bovine tuberculosis. This bacterium is the causative agent of classic bovine tuberculosis, but it can also cause the disease in humans, especially if contaminated milk is consumed without prior pasteurization. The Mycobacterium bovis complex is a diverse group of species, serovars and morphotypes that cause tuberculosis-like diseases in animals and humans. Pasteurization of milk is a major preventitive factor in transmission of bovine tuberculosis to humans. However, spreading the disease through milk and dairy products is still a concern in underdeveloped countries where pasteurization is not practiced. The pathology in cows is similar to the pathology of Mycobacterium tuberculosis in humans, with pulmonary TB leading to chronic debilitation, coughing, and further systemic spread to other organs. In addition, 1 to 2% of infected cows develop mycobacterial mastitis that results in shedding of the bacteria into the milk.

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BLASTN Alignment.txt

Subject: NC_010397:4387500 Mycobacterium abscessus chromosome Chromosome, complete sequence

Lineage: Mycobacterium abscessus; Mycobacterium; Mycobacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: Mycobacterium abscessus, formerly Mycobacterium chelonae subsp. abscessus, is a rapid-growing Mycobacterium sp., commonly isolated from soil and water. This organism causes a chronic lung infection, similar to tuberculosis, in patients with cystic fibrosis. Mycobacterium abscessus also causes wound and ear infections, and in immunosuppressed patients causes a generalized skin infection. This organism is very resistant to many commonly used antibiotics, which makes treatment difficult.