Pre_GI: SWBIT SVG BLASTN

Query: NC_011898:4044500 Clostridium cellulolyticum H10, complete genome

Lineage: Clostridium cellulolyticum; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: A non-ruminal mesophilic cellulolytic bacterium originally isolated from decayed grass compost. This genus comprises about 150 metabolically diverse species of anaerobes that are ubiquitous in virtually all anoxic habitats where organic compounds are present, including soils, aquatic sediments and the intestinal tracts of animals and humans. This shape is attributed to the presence of endospores that develop under conditions unfavorable for vegetative growth and distend single cells terminally or sub-terminally. Spores germinate under conditions favorable for vegetative growth, such as anaerobiosis and presence of organic substrates. It is believed that present day Mollicutes (Eubacteria) have evolved regressively (i.e., by genome reduction) from gram-positive clostridia-like ancestors with a low GC content in DNA. Clostridium cellulolyticum is a mesophilic cellulolytic bacterium. Cellulose-degradation by C. cellulolyticum has been extensively studied. The cellulolytic enzymes of this organism are bound to a protein scaffold in an extracellular multienzyme complex called a cellulosome.

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BLASTN Alignment.txt

Subject: NC_012781:2148478 Eubacterium rectale ATCC 33656, complete genome

Lineage: Eubacterium rectale; Eubacterium; Eubacteriaceae; Clostridiales; Firmicutes; Bacteria

General Information: Eubacterium rectale ATCC 33656 was isolated from human feces. This genus has been isolated as normal flora from feces, rumen, and periodontal tissue. Eubacterium spp. are thought to play a beneficial role in maintaining the normal ecology of the large intestine, in part by producing chemicals like butyric acid which act to inhibit the growth of other bacteria. These organisms are occasionally isolated from wounds and abscesses and may be an opportunistic pathogen. This genus has also been isolated from sewage and soil.