Pre_GI: SWBIT SVG BLASTN

Query: NC_011898:351792 Clostridium cellulolyticum H10, complete genome

Lineage: Clostridium cellulolyticum; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: A non-ruminal mesophilic cellulolytic bacterium originally isolated from decayed grass compost. This genus comprises about 150 metabolically diverse species of anaerobes that are ubiquitous in virtually all anoxic habitats where organic compounds are present, including soils, aquatic sediments and the intestinal tracts of animals and humans. This shape is attributed to the presence of endospores that develop under conditions unfavorable for vegetative growth and distend single cells terminally or sub-terminally. Spores germinate under conditions favorable for vegetative growth, such as anaerobiosis and presence of organic substrates. It is believed that present day Mollicutes (Eubacteria) have evolved regressively (i.e., by genome reduction) from gram-positive clostridia-like ancestors with a low GC content in DNA. Clostridium cellulolyticum is a mesophilic cellulolytic bacterium. Cellulose-degradation by C. cellulolyticum has been extensively studied. The cellulolytic enzymes of this organism are bound to a protein scaffold in an extracellular multienzyme complex called a cellulosome.

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BLASTN Alignment.txt

Subject: NC_002967:800109 Treponema denticola ATCC 35405, complete genome

Lineage: Treponema denticola; Treponema; Spirochaetaceae; Spirochaetales; Spirochaetes; Bacteria

General Information: Treponema denticola ATCC 35405 was isolated from a human periodontal pocket. Associated with periodontal disease. This organism is a member of the spirochaetales and is a motile, slender, helically shaped flexible organism. Obligately anaerobic growth occurs at 30-42°C, with a pH of 6.5-8.0. The bacterium is commonly found in the oral cavity of humans and often associated with periodontal disease, an inflammation of the gum tissue that frequently precedes bone resorbtion and subsequent tooth loss.