Pre_GI: SWBIT SVG BLASTN

Query: NC_011898:874457 Clostridium cellulolyticum H10, complete genome

Lineage: Clostridium cellulolyticum; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: A non-ruminal mesophilic cellulolytic bacterium originally isolated from decayed grass compost. This genus comprises about 150 metabolically diverse species of anaerobes that are ubiquitous in virtually all anoxic habitats where organic compounds are present, including soils, aquatic sediments and the intestinal tracts of animals and humans. This shape is attributed to the presence of endospores that develop under conditions unfavorable for vegetative growth and distend single cells terminally or sub-terminally. Spores germinate under conditions favorable for vegetative growth, such as anaerobiosis and presence of organic substrates. It is believed that present day Mollicutes (Eubacteria) have evolved regressively (i.e., by genome reduction) from gram-positive clostridia-like ancestors with a low GC content in DNA. Clostridium cellulolyticum is a mesophilic cellulolytic bacterium. Cellulose-degradation by C. cellulolyticum has been extensively studied. The cellulolytic enzymes of this organism are bound to a protein scaffold in an extracellular multienzyme complex called a cellulosome.

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Subject: NC_012846:1888000 Bartonella grahamii as4aup, complete genome

Lineage: Bartonella grahamii; Bartonella; Bartonellaceae; Rhizobiales; Proteobacteria; Bacteria

General Information: Bartonella grahamii (strain as4aup) is Gram-negative bacterium isolated from a wood mouse (Apodemus sylvaticus) in central Sweden. Bartonella are human and animal pathogens which infect erythrocytes and can cause angiogenic lesions. These organisms cause diseases in humans such as Oroya fever, Trench fever, endocarditis, and Cat Scratch disease. Transmission of this organism is via the bite of a blood-sucking arthropod. Bartonella grahamii can be isolated from the blood of rodents and is found world wide. Fleas may be the transmission vector for Bartonella grahamii to other rodents. Human disease appears to be rare and associated with an immunocompromised state.