Pre_GI: SWBIT SVG BLASTN

Query: NC_011898:874457 Clostridium cellulolyticum H10, complete genome

Lineage: Clostridium cellulolyticum; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: A non-ruminal mesophilic cellulolytic bacterium originally isolated from decayed grass compost. This genus comprises about 150 metabolically diverse species of anaerobes that are ubiquitous in virtually all anoxic habitats where organic compounds are present, including soils, aquatic sediments and the intestinal tracts of animals and humans. This shape is attributed to the presence of endospores that develop under conditions unfavorable for vegetative growth and distend single cells terminally or sub-terminally. Spores germinate under conditions favorable for vegetative growth, such as anaerobiosis and presence of organic substrates. It is believed that present day Mollicutes (Eubacteria) have evolved regressively (i.e., by genome reduction) from gram-positive clostridia-like ancestors with a low GC content in DNA. Clostridium cellulolyticum is a mesophilic cellulolytic bacterium. Cellulose-degradation by C. cellulolyticum has been extensively studied. The cellulolytic enzymes of this organism are bound to a protein scaffold in an extracellular multienzyme complex called a cellulosome.

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Subject: NC_006677:1431500 Gluconobacter oxydans 621H, complete genome

Lineage: Gluconobacter oxydans; Gluconobacter; Acetobacteraceae; Rhodospirillales; Proteobacteria; Bacteria

General Information: Industrially useful bacterium. Gluconobacter oxydans is a member of the Acetobacteraceae family within the alpha proteobacteria and can be isolated from flowers, fruits, and fermented beverages. This organism uses membrane-associated dehydrogenases to incompletely oxidize a wide variety of carbohydrates and alcohols. Oxidation occurs in the periplasm with the products being released into the medium via outer membrane porins and the electrons entering the electron transport chain. Able to oxidize large amounts of substrates, making it useful for industrial purposes. Among other applications, it has been used to produce 2-ketogluconic for iso-ascorbic acid production, 5-ketogluconic acid from glucose for tartaric acid production, and L-sorbose from sorbitol for vitamin C synthesis.