Pre_GI: SWBIT SVG BLASTN

Query: NC_011896:332939 Mycobacterium leprae Br4923, complete genome

Lineage: Mycobacterium leprae; Mycobacterium; Mycobacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: This strain was isolated from a human skin biopsy in Brazil, and passaged in nude mice and armadillos. The bacterium is a close relative of M. tuberculosis. However, compared to the latter, the genome of M. leprae is smaller due to reductive genome evolution, with many important metabolic activities including siderophore production, part of the oxidative chain, most of the microaerophilic and anaerobic respiratory chains, and numerous catabolic systems and their regulatory circuits eliminated due to extensive recombination events between dispersed repetitive sequences. It is evident that this species has undergone massive genome reduction over time as a result of its parasitic nature, discarding more than half its genes and rendering it the most striking example of genome reduction in a microbial pathogen.

Subject: NC_014148:3368519 Planctomyces limnophilus DSM 3776 chromosome, complete genome

Lineage: Planctomyces limnophilus; Planctomyces; Planctomycetaceae; Planctomycetales; Planctomycetes; Bacteria

General Information: Isolation: Surface water; Temp: Mesophile; Habitat: Fresh water, Marine; Isolation: surface water. Planctomyces limnophilus is a member of the order Planctomycetales, a group of budding mostly aquatic microorganisms lacking peptidoglycan and representing a phylogenetically distinct lineage within the domain Bacteria. The planctomycetes share a number of morphological features, having spherical or ovoid cells which bear crateriform structures and, in some cases, nonprosthecate appendages. The is the type strain and was isolated from the surface waters of a German lake.