Query: NC_011894:6793497 Methylobacterium nodulans ORS 2060, complete genome
Lineage: Methylobacterium nodulans; Methylobacterium; Methylobacteriaceae; Rhizobiales; Proteobacteria; Bacteria
General Information: Methylobacterium nodulans was isolated from root nodules from the legume Crotalaria, a large Fabaceae group found in Africa. Methylobacterium nodulans fixes nitrogen and can grow with C1 compounds, such as methanol and formate, as a sole carbon source.
Subject: NC_003318:183914 Brucella melitensis 16M chromosome II, complete sequence
Lineage: Brucella melitensis; Brucella; Brucellaceae; Rhizobiales; Proteobacteria; Bacteria
General Information: This strain was isolated from an infected goat and is pathogenic in humans. Causes brucellosis and undulant fever. They are highly infectious, and can be spread through contact with infected animal products or through the air, making them a potential bioterrorism agent. Once the organism has entered the body, it can become intracellular, and enter the blood and lymphatic regions, multiplying inside phagocytes before eventually causing bacteremia (spread of bacteria through the blood). Virulence may depend on a type IV secretion system which may promote intracellular growth by secreting important effector molecules. This organism is a facultative intracellular bacteria that causes abortion in wild and domestic animals, usually goats or sheep, and undulant fever in humans. Brucellosis is a major health problem in the Mediterranean region and parts of Asia, Africa, and Latin America, where it causes severe economic losses. The disease is transmitted to humans by nonpasteurized milk and milk products or by direct contact with infected animals or carcasses.