Query: NC_011745:2399313 Escherichia coli ED1a chromosome, complete genome Lineage: Escherichia coli; Escherichia; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria General Information: Isolated in the 2000s from the faeces of a healthy man in France. This organism was named for its discoverer, Theodore Escherich, and is one of the premier model organisms used in the study of bacterial genetics, physiology, and biochemistry. This enteric organism is typically present in the lower intestine of humans, where it is the dominant facultative anaerobe present, but it is only one minor constituent of the complete intestinal microflora. E. coli, is capable of causing various diseases in its host, especially when they acquire virulence traits. E. coli can cause urinary tract infections, neonatal meningitis, and many different intestinal diseases, usually by attaching to the host cell and introducing toxins that disrupt normal cellular processes.
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General Information: This bacterium was isolated from a bovine rumen. Succinic acid producing bacterium. This bacterium is able to produce a large amount of succinic acid from readily available agricultural byproducts. Succinic acid is an important component in the manufacture of synthetic resins and biodegradable polymers. Mannheimia succiniciproducens can grow on media which includes whey, a byproduct of the cheese industry which is normally discarded, and corn steep liquor (CSL), which is a byproduct of corn starch production. The organism has been able to produce production-level amounts of succinic acid in both batch and continuous cultures in media containing these inexpensive components.