Query: NC_011658:5239509 Bacillus cereus AH187 chromosome, complete genome Lineage: Bacillus cereus; Bacillus; Bacillaceae; Bacillales; Firmicutes; Bacteria General Information: This strain was isolated from the vomit of a person having eaten cooked rice by the Public Health Laboratory Service (PHLS), London, UK. The isolate was associated with an emetic outbreak in 1972. This organism is a soil-dwelling opportunistic pathogen that causes food poisoning in infected individuals. The rapid onset is characterized by nausea and vomiting while the late onset is characterized by diarrhea and abdominal pain. The emetic disease is caused by a small stable dodecadepsipeptide cerulide whereas the diarrheal disease is caused by a heat labile enterotoxin. Some strains produce a potent cytotoxin that forms a pore in the membrane of eukaryotic cells and causes necrotic enteritis (death of intestinal epithelial cells) while the unique tripartite membrane lytic toxin hemolysin BL contributes to the diarrheal disease and destructive infections of the eye.
- Sequence; - BLASTN hit (Low score = Light, High score = Dark) - hypothetical protein; - cds: hover for description
General Information: Edwardsiella tarda is a Gram-negative member of the normal gut microflora of fish, humans, chickens and other animals. This organism is also a serious pathogen of marine and freshwater fish and has been isolated from channel catfish, Japanese eels, flounder, tilapia, and other economically important fish. Infection by this organism is characterized by septicemia, internal abscesses, and skin lesions. This disease is often associated with poor water quality and mortality in aquaculture can be high. Edwardsiella tarda also causes opportunistic infections in humans, most commonly gastroenteritis and wound infections. However, this organism has been isolated from cases of septicemia and meningitis, primarily in immunocompromised patients.