Pre_GI: SWBIT SVG BLASTN

Query: NC_011658:3144000 Bacillus cereus AH187 chromosome, complete genome

Lineage: Bacillus cereus; Bacillus; Bacillaceae; Bacillales; Firmicutes; Bacteria

General Information: This strain was isolated from the vomit of a person having eaten cooked rice by the Public Health Laboratory Service (PHLS), London, UK. The isolate was associated with an emetic outbreak in 1972. This organism is a soil-dwelling opportunistic pathogen that causes food poisoning in infected individuals. The rapid onset is characterized by nausea and vomiting while the late onset is characterized by diarrhea and abdominal pain. The emetic disease is caused by a small stable dodecadepsipeptide cerulide whereas the diarrheal disease is caused by a heat labile enterotoxin. Some strains produce a potent cytotoxin that forms a pore in the membrane of eukaryotic cells and causes necrotic enteritis (death of intestinal epithelial cells) while the unique tripartite membrane lytic toxin hemolysin BL contributes to the diarrheal disease and destructive infections of the eye.

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BLASTN Alignment.txt

Subject: NC_008228:3679949 Pseudoalteromonas atlantica T6c, complete genome

Lineage: Pseudoalteromonas atlantica; Pseudoalteromonas; Pseudoalteromonadaceae; Alteromonadales; Proteobacteria; Bacteria

General Information: Isolated from a biofilm from San Diego Bay in California. Marine biofilm bacterium associated with shell disease in shellfish. A common marine bacterium that exists both in the water column, and in biofilms attached to surfaces. This organism produces a well characterized, commercially important agarase. Pseudoalteromonas atlantica has been isolated from lesions on crabs with shell disease. Shell disease is characterized by progressive degradation of the shell, often leading to an infection of the hemolymph (blood) and may be caused by Pseudoalteromonas, Alteromonas, Vibrio, or other marine organisms. In addition to producing extracellular enzymes which attack the shell, Pseudoalteromonas atlantica produces a the lipopolysaccharide which has been shown to be a potential virulence factor in shell disease.