Query: NC_011375:749693 Streptococcus pyogenes NZ131 chromosome, complete genome
Lineage: Streptococcus pyogenes; Streptococcus; Streptococcaceae; Lactobacillales; Firmicutes; Bacteria
General Information: This strain is a serotype M49 strain isolated from a patient with acute glomerulonephritis. Streptococci are Gram-positive, nonmotile, nonsporeforming, catalase-negative cocci that occur in pairs or chains. Members of this genus vary widely in pathogenic potential. Most streptococci are facultative anaerobes, and some are obligate anaerobes. Serologic grouping is based on antigenic differences in cell wall carbohydrates, in cell wall pili-associated protein, and in the polysaccharide capsule in group B streptococci. This organism is a member of the normal human nasopharyngeal flora. S. pyogenes is a group A streptococcus and is the leading cause of uncomplicated bacterial pharyngitis and tonsillitis. This organism is commonly referred to by the lay press as "flesh eating bacteria".