Query: NC_011375:1607656 Streptococcus pyogenes NZ131 chromosome, complete genome
Lineage: Streptococcus pyogenes; Streptococcus; Streptococcaceae; Lactobacillales; Firmicutes; Bacteria
General Information: This strain is a serotype M49 strain isolated from a patient with acute glomerulonephritis. Streptococci are Gram-positive, nonmotile, nonsporeforming, catalase-negative cocci that occur in pairs or chains. Members of this genus vary widely in pathogenic potential. Most streptococci are facultative anaerobes, and some are obligate anaerobes. Serologic grouping is based on antigenic differences in cell wall carbohydrates, in cell wall pili-associated protein, and in the polysaccharide capsule in group B streptococci. This organism is a member of the normal human nasopharyngeal flora. S. pyogenes is a group A streptococcus and is the leading cause of uncomplicated bacterial pharyngitis and tonsillitis. This organism is commonly referred to by the lay press as "flesh eating bacteria".
Subject: NC_011134:1854868 Streptococcus equi subsp. zooepidemicus str. MGCS10565, complete
Lineage: Streptococcus equi; Streptococcus; Streptococcaceae; Lactobacillales; Firmicutes; Bacteria
General Information: Streptococcus equi subsp. zooepidemicus str. MGCS10565 was responsible for a large and severe epidemic outbreak of poststreptococcal glomerulonephritis. Streptococci are Gram-positive, nonmotile, nonsporeforming, catalase-negative cocci that occur in pairs or chains. Members of this genus vary widely in pathogenic potential. Most streptococci are facultative anaerobes, and some are obligate anaerobes. Serologic grouping is based on antigenic differences in cell wall carbohydrates, in cell wall pili-associated protein, and in the polysaccharide capsule in group B streptococci. Streptococcus equi is comprised of three subspecies equi, zooepidemicus and ruminatorum all of which cause disease in horses, sheep or goats. Streptococcus equi subsp. zooepidemicus has also been isolated from clinical cases in humans and other animals. This species is a Lancefield C group bacterium.