Query: NC_011374:325507 Ureaplasma urealyticum serovar 10 str. ATCC 33699 chromosome,
Lineage: Ureaplasma urealyticum; Ureaplasma; Mycoplasmataceae; Mycoplasmatales; Tenericutes; Bacteria
General Information: Causes a wide range of infections of the urogenital or respiratory tracts. Ureaplasma urealyticum is part of the normal flora of the human urogenital tract. This organism, however, can cause urethritis and has been associated with spontaneous abortion, premature birth, meningitis, and a severe respiratory disease of premature infants. U. urealyticum strains exhibit antigenic heterogeneity. Isolates obtained from human urogenital tract have been classified into 14 recognized serovars which show no serological cross-reactivity with ureaplasmas from other hosts and uniquely express human immuoglobulin A1 protease activity.
Subject: NC_012633:928500 Rickettsia africae ESF-5, complete genome
Lineage: Rickettsia africae; Rickettsia; Rickettsiaceae; Rickettsiales; Proteobacteria; Bacteria
General Information: This organism was isolated from a cattle tick, Amblyomma variegatum, collected in Ethiopia. This organism, a member of the spotted fever group of the Rickettsiales, is found in sub-Saharan Africa and the Caribbean. Rickettsia africae causes a flu-like illness, characterized by a mild fever and severe headache, without the skin rash common to other spotted fever group Rickettsia species. Members of this genus, like other Rickettsial organisms such as Neorickettsia and Anaplasma, are obligate intracellular pathogens. In both groups, the bacteria are transmitted via an insect, usually a tick, to a host organism where they target endothelial cells and sometimes macrophages. They attach via an adhesin, rickettsial outer membrane protein A, and are internalized where they persist as cytoplasmically free organisms.