Query: NC_011374:202936 Ureaplasma urealyticum serovar 10 str. ATCC 33699 chromosome, Lineage: Ureaplasma urealyticum; Ureaplasma; Mycoplasmataceae; Mycoplasmatales; Tenericutes; Bacteria General Information: Causes a wide range of infections of the urogenital or respiratory tracts. Ureaplasma urealyticum is part of the normal flora of the human urogenital tract. This organism, however, can cause urethritis and has been associated with spontaneous abortion, premature birth, meningitis, and a severe respiratory disease of premature infants. U. urealyticum strains exhibit antigenic heterogeneity. Isolates obtained from human urogenital tract have been classified into 14 recognized serovars which show no serological cross-reactivity with ureaplasmas from other hosts and uniquely express human immuoglobulin A1 protease activity.
- Sequence; - BLASTN hit (Low score = Light, High score = Dark) - hypothetical protein; - cds: hover for description
General Information: Causative agent for Rocky Mountain Spotted Fever. This organism was first identified by Dr. Howard Rickets as the causative agent of Rocky Mountain Spotted Fever, which was originally named for its geographic distribution at the time, it is now known to be widespread throughout the North American continent. This bacterium is an obligate intracellular pathogen that infects primarily the vascular endothelium, and occasionally smooth muscle tissue. It is passed to the human host from a tick bite, and the tick acts as both a natural reservoir and a vector for disease transmission. Once the organism is endocytosed by the host cell, it quickly escapes the phagozome, and replicates intracellularly, causing cell death and tissue damage. The disease is characterized by a spotted rash and has a high mortality rate if left untreated.