Pre_GI: SWBIT SVG BLASTN

Query: NC_011283:942594 Klebsiella pneumoniae 342 chromosome, complete genome

Lineage: Klebsiella pneumoniae; Klebsiella; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: Klebsiella pneumoniae 342 was isolated from the stem tissue of Zea mays. This strain fixes atmospheric nitrogen and may be able to provide nitrogen, in the form of ammonia, to plant cells. This organism is the most medically important organism within the genus Klebsiella. It is an environmental organism found in water, soil, and on the surface of plants. Several strains have been isolated from plant tissues and are nitrogen-fixing endophytes that may be a source of nitrogen for the plant. Other strains can become opportunistic pathogens which infect humans, and typically causes hospital-acquired infections in immunocompromised patients. Major sites of infection include the lungs, where it causes a type of pneumonia, and urinary tract infections. Klebsiella can also enter the bloodstream (bacterimia) and cause sepsis. The pathogen can also infect animals and cause inflammation of the uterus in horses as well as more generalized infections in other mammals. This organism expresses numerous pathogenicity factors, including multiple adhesins, capsular polysaccharide, siderophores, and lipopolysaccharide for the evasion of host defenses. The multiple antibiotic resistance genes carried on the chromosome inhibit efforts to clear the organism from infected patients via antibiotic use.

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BLASTN Alignment.txt

Subject: NC_011988:924721 Agrobacterium vitis S4 chromosome 2, complete genome

Lineage: Agrobacterium vitis; Agrobacterium; Rhizobiaceae; Rhizobiales; Proteobacteria; Bacteria

General Information: Agrobacterium vitis is the causative agent of crown gall disease in grapes. Agrobacterium are Gram-negative, motile, soil-dwelling plant pathogens with the species name given based on the disease phenotype associated with the bacteria. Disease causing Agrobacterium spp. possess a tumor-inducing (Ti) plasmid, which carries genes for the formation of opines. A segment of the Ti plasmid gets transferred to the plant cell and integrates into the host cell genome. The plant cell then starts synthesizing opines, which can be catabolized by Agrobacterium spp, but not by the plant cells.